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Tramadol works by binding to opioid receptors in the brain, which helps to block pain signals and provide relief.

In addition to its opioid activity, tramadol also has some effects on the neurotransmitters norepinephrine and serotonin in the brain, which may contribute to its analgesic effects. It is important to note that tramadol is considered a controlled substance and carries a risk of dependence, addiction, and abuse. It is typically prescribed for short-term use or under close monitoring in chronic pain situations.