Leucovorincalcium injection is used to protect from the harmful effects of anti-cancermedicines and is also used at the time of overdose. leucovorincalcium 50mg injection was injected slowly into the vein under the experienced doctor. Beforetaking this injection tell all medical history to the doctor like liver andkidney problems. After taking this injection a site reaction will be seen thepain, redness, and swelling. Pregnant and breastfeeding women should consultthe doctor before beginning the treatment.